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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SACS GDSC1000 pan-cancer AAC 0.082 0.05
mRNA POMGNT1 FIMM pan-cancer AAC -0.35 0.05
mRNA PTPN11 FIMM pan-cancer AAC 0.34 0.05
mRNA HIRA GDSC1000 pan-cancer AAC 0.073 0.05
mRNA CRHR2 FIMM pan-cancer AAC 0.39 0.05
mRNA HYAL3 FIMM pan-cancer AAC 0.39 0.05
mRNA RBBP8NL GDSC1000 pan-cancer AAC -0.069 0.05
mRNA SND1 GDSC1000 pan-cancer AAC -0.075 0.05
mRNA DCAF13 FIMM pan-cancer AAC 0.34 0.05
mRNA CTRC GDSC1000 pan-cancer AAC -0.069 0.05
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