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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA T FIMM pan-cancer AAC -0.33 0.05
mRNA GRP FIMM pan-cancer AAC 0.37 0.05
mRNA MYH4 GDSC1000 pan-cancer AAC -0.073 0.05
mRNA ZNF675 GDSC1000 pan-cancer AAC 0.076 0.05
mRNA EID2 GDSC1000 pan-cancer AAC 0.072 0.05
mRNA SPATA31D3 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA MBLAC2 GDSC1000 pan-cancer AAC 0.078 0.05
mRNA GZMH FIMM pan-cancer AAC -0.39 0.05
mRNA UBE3D GDSC1000 pan-cancer AAC 0.076 0.05
mRNA SEC31A GDSC1000 pan-cancer AAC -0.073 0.05
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