1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA NPW GDSC1000 pan-cancer AAC 0.073 0.05
mRNA PIGF FIMM pan-cancer AAC -0.35 0.05
mRNA LHX1 FIMM pan-cancer AAC 0.36 0.05
mRNA ZNF35 FIMM pan-cancer AAC -0.35 0.05
mRNA MMD GDSC1000 pan-cancer AAC 0.077 0.05
mRNA TOB2 GDSC1000 pan-cancer AAC -0.071 0.05
mRNA ZKSCAN3 GDSC1000 pan-cancer AAC 0.071 0.05
mRNA DYNLRB2 GDSC1000 pan-cancer AAC -0.074 0.05
mRNA C10orf120 GDSC1000 pan-cancer AAC 0.071 0.05
mRNA ZNF710 GDSC1000 pan-cancer AAC -0.073 0.05
Download CSV