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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SLFN12L GDSC1000 pan-cancer AAC 0.074 0.05
mRNA ELK4 GDSC1000 pan-cancer AAC -0.079 0.05
mRNA GPX5 GDSC1000 pan-cancer AAC -0.072 0.05
mRNA FLNB GDSC1000 pan-cancer AAC 0.089 0.05
mRNA IL18BP GDSC1000 pan-cancer AAC -0.071 0.05
mRNA SLC13A4 FIMM pan-cancer AAC 0.36 0.05
mRNA PAPOLG GDSC1000 pan-cancer AAC 0.078 0.05
mRNA CPOX FIMM pan-cancer AAC -0.35 0.05
mRNA NCOA7 GDSC1000 pan-cancer AAC 0.076 0.05
mRNA AQP10 GDSC1000 pan-cancer AAC -0.071 0.05
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