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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA CLPS GDSC1000 pan-cancer AAC -0.071 0.04
mRNA TIAM1 FIMM pan-cancer AAC -0.35 0.04
mRNA SEMG1 FIMM pan-cancer AAC 0.39 0.04
mRNA PCSK4 GDSC1000 pan-cancer AAC 0.071 0.05
mRNA YTHDC1 GDSC1000 pan-cancer AAC 0.079 0.05
mRNA GYG1 GDSC1000 pan-cancer AAC -0.073 0.05
mRNA SMDT1 GDSC1000 pan-cancer AAC -0.083 0.05
mRNA PRIM1 GDSC1000 pan-cancer AAC 0.077 0.05
mRNA BCL2L1 GDSC1000 pan-cancer AAC -0.08 0.05
mRNA ZNF101 GDSC1000 pan-cancer AAC -0.092 0.05
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