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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF541 GDSC1000 pan-cancer AAC -0.07 0.04
mRNA C1orf210 GDSC1000 pan-cancer AAC -0.081 0.04
mRNA SLC1A7 GDSC1000 pan-cancer AAC 0.069 0.04
mRNA NT5E FIMM pan-cancer AAC -0.38 0.04
mRNA ASPG GDSC1000 pan-cancer AAC 0.071 0.04
mRNA KRTAP10-8 GDSC1000 pan-cancer AAC -0.072 0.04
mRNA BTRC GDSC1000 pan-cancer AAC 0.073 0.04
mRNA CIITA GDSC1000 pan-cancer AAC -0.087 0.04
mRNA RSPH1 GDSC1000 pan-cancer AAC -0.077 0.04
mRNA RPL27 GDSC1000 pan-cancer AAC 0.075 0.04
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