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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA TRAK1 GDSC1000 pan-cancer AAC -0.077 0.04
mRNA PAK5 FIMM pan-cancer AAC -0.37 0.04
mRNA C1orf74 GDSC1000 pan-cancer AAC 0.077 0.04
mRNA MC5R FIMM pan-cancer AAC 0.34 0.04
mRNA ZC3H13 FIMM pan-cancer AAC 0.41 0.04
mRNA EHF GDSC1000 pan-cancer AAC -0.091 0.04
mRNA OR13C4 GDSC1000 pan-cancer AAC -0.073 0.04
mRNA MTHFD1 GDSC1000 pan-cancer AAC 0.071 0.04
mRNA LRIG2 FIMM pan-cancer AAC 0.34 0.04
mRNA SLC26A2 FIMM pan-cancer AAC 0.34 0.04
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