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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SLC37A1 GDSC1000 pan-cancer AAC -0.083 0.04
mRNA NLGN3 GDSC1000 pan-cancer AAC -0.08 0.04
mRNA ATF6B GDSC1000 pan-cancer AAC -0.078 0.04
mRNA GTF2F2 GDSC1000 pan-cancer AAC 0.075 0.04
mRNA ATP8B4 GDSC1000 pan-cancer AAC 0.074 0.04
mRNA BBS2 GDSC1000 pan-cancer AAC 0.075 0.04
mRNA UTP18 GDSC1000 pan-cancer AAC 0.074 0.04
mRNA ARHGEF11 GDSC1000 pan-cancer AAC -0.076 0.04
mRNA LYG1 GDSC1000 pan-cancer AAC 0.072 0.04
mRNA FURIN GDSC1000 pan-cancer AAC -0.072 0.04
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