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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA UGT2B7 GDSC1000 pan-cancer AAC 0.093 0.04
mRNA FEV FIMM pan-cancer AAC -0.34 0.04
mRNA SCARB2 GDSC1000 pan-cancer AAC -0.089 0.04
mRNA ROGDI GDSC1000 pan-cancer AAC 0.078 0.04
mRNA CXCL3 FIMM pan-cancer AAC -0.36 0.04
mRNA SYT7 GDSC1000 pan-cancer AAC -0.081 0.04
mRNA ANKRD54 GDSC1000 pan-cancer AAC -0.08 0.04
mRNA ZNF33B GDSC1000 pan-cancer AAC 0.076 0.04
mRNA EIF3F GDSC1000 pan-cancer AAC -0.074 0.04
mRNA BAZ2A GDSC1000 pan-cancer AAC -0.076 0.04
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