1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM86B GDSC1000 pan-cancer AAC 0.075 0.04
mRNA NTN4 GDSC1000 pan-cancer AAC 0.088 0.04
mRNA RAB3A GDSC1000 pan-cancer AAC -0.078 0.04
mRNA TP53INP1 GDSC1000 pan-cancer AAC -0.076 0.04
mRNA FBXO27 GDSC1000 pan-cancer AAC 0.081 0.04
mRNA ARHGAP32 GDSC1000 pan-cancer AAC -0.091 0.04
mRNA EMILIN2 GDSC1000 pan-cancer AAC 0.074 0.04
mRNA SPACA1 GDSC1000 pan-cancer AAC -0.072 0.04
mRNA TERF1 FIMM pan-cancer AAC 0.35 0.04
mRNA RPS6KB2 GDSC1000 pan-cancer AAC -0.075 0.04
Download CSV