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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGAP27 GDSC1000 pan-cancer AAC -0.091 0.04
mRNA MARK2 GDSC1000 pan-cancer AAC -0.079 0.04
mRNA RASD2 GDSC1000 pan-cancer AAC 0.075 0.04
mRNA ARL1 FIMM pan-cancer AAC 0.43 0.04
mRNA ITGB2 GDSC1000 pan-cancer AAC 0.086 0.04
mRNA OR10A3 GDSC1000 pan-cancer AAC 0.072 0.04
mRNA TCERG1 GDSC1000 pan-cancer AAC -0.081 0.04
mRNA AKT1 GDSC1000 pan-cancer AAC -0.075 0.04
mRNA MON2 GDSC1000 pan-cancer AAC -0.073 0.04
mRNA GPR15 FIMM pan-cancer AAC -0.35 0.04
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