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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA HDGF GDSC1000 pan-cancer AAC -0.075 0.04
mRNA PLEKHA5 GDSC1000 pan-cancer AAC -0.081 0.04
mRNA GPX6 GDSC1000 pan-cancer AAC -0.075 0.04
mRNA FES GDSC1000 pan-cancer AAC 0.084 0.04
mRNA FERMT2 GDSC1000 pan-cancer AAC 0.1 0.04
mRNA SNX6 GDSC1000 pan-cancer AAC 0.079 0.04
mRNA TRPM1 FIMM pan-cancer AAC 0.35 0.04
mRNA UPB1 GDSC1000 pan-cancer AAC 0.074 0.04
mRNA RASSF4 GDSC1000 pan-cancer AAC 0.08 0.04
mRNA KCNB1 GDSC1000 pan-cancer AAC -0.076 0.04
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