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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA DLG3 FIMM pan-cancer AAC 0.54 0.004
mRNA NR2F1 FIMM pan-cancer AAC 0.56 0.0005
mRNA ZNF107 FIMM pan-cancer AAC 0.56 0.007
mRNA CDH5 FIMM pan-cancer AAC 0.57 3e-05
mRNA CLDN16 FIMM pan-cancer AAC 0.57 0.002
mRNA LHX1 FIMM pan-cancer AAC 0.58 0.0001
mRNA CUBN FIMM pan-cancer AAC 0.59 3e-05
mRNA KCNJ13 FIMM pan-cancer AAC 0.59 2e-05
mRNA REST FIMM pan-cancer AAC 0.59 5e-05
mRNA CARD8 FIMM pan-cancer AAC 0.61 0.01
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