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Compounds/
KU-55933

KU-55933

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	KU-55933
PharmacoGx	KU-55933

External IDs

Database	Identifier
Smiles:	C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
Inchikey:	XRKYMMUGXMWDAO-UHFFFAOYSA-N
Pubchem:	5278396

Annotated Targets

ATM, PRKDC

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KU-55933

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NET1	GDSC1000	pan-cancer	AAC	0.16	9e-05
mRNA	LY6G5C	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	SCN8A	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	MDFI	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	UBL4B	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	TM6SF1	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	EXOSC7	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	GNPDA2	GDSC1000	pan-cancer	AAC	-0.14	0.0002
mRNA	FAM175A	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	BATF	CTRPv2	pan-cancer	AAC	0.14	0.0002

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