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AMG-706

AMG-706

Synonyms

Sources	Names Used
GDSC1000	AMG-706
FIMM	Motesanib
PharmacoGx	AMG-706

External IDs

Database	Identifier
Smiles:	CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
Inchikey:	RAHBGWKEPAQNFF-UHFFFAOYSA-N
Pubchem:	11667893

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AMG-706

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF433	GDSC1000	pan-cancer	AAC	0.096	0.009
mRNA	ZNF442	GDSC1000	pan-cancer	AAC	0.083	0.02
mRNA	ZNF45	GDSC1000	pan-cancer	AAC	0.085	0.02
mRNA	ZNF467	FIMM	pan-cancer	AAC	0.48	0.002
mRNA	ZNF469	GDSC1000	pan-cancer	AAC	0.09	0.01
mRNA	ZNF514	GDSC1000	pan-cancer	AAC	-0.079	0.03
mRNA	ZNF556	GDSC1000	pan-cancer	AAC	0.14	7e-05
mRNA	ZNF562	GDSC1000	pan-cancer	AAC	0.097	0.005
mRNA	ZNF620	GDSC1000	pan-cancer	AAC	-0.092	0.01
mRNA	ZNF622	GDSC1000	pan-cancer	AAC	0.083	0.02

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