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VX-702

Synonyms

SourcesNames Used
GDSC1000VX-702
PharmacoGx VX-702

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F
Inchikey: FYSRKRZDBHOFAY-UHFFFAOYSA-N
Pubchem: 10341154

Annotated Targets

MAPK11, MAPK12, MAPK14, TNF, IL1B, IL6

FDA Approval Status

Not Approved
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Top molecular features associated with response to VX-702


Feature TypeStandardized
Nominal ANOVA
mRNA PXDC1 GDSC1000 pan-cancer AAC -0.1 0.03
mRNA SUPT7L GDSC1000 pan-cancer AAC 0.077 0.03
mRNA AMBP GDSC1000 pan-cancer AAC 0.081 0.03
mRNA EMSY GDSC1000 pan-cancer AAC -0.08 0.03
mRNA RAB7A GDSC1000 pan-cancer AAC -0.084 0.03
mRNA KCNK9 GDSC1000 pan-cancer AAC -0.076 0.03
mRNA CCND1 GDSC1000 pan-cancer AAC -0.099 0.03
mRNA HIGD1C GDSC1000 pan-cancer AAC -0.078 0.03
mRNA WDR72 GDSC1000 pan-cancer AAC 0.079 0.03
mRNA KAT2A GDSC1000 pan-cancer AAC 0.077 0.03
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