PharmacoDB

Sources

Names Used

17-AAG

Tanespimycin

tanespimycin

PharmacoGx

17-AAG

Database	Identifier
Smiles:	CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Inchikey:	AYUNIORJHRXIBJ-TXHRRWQRSA-N
Pubchem:	6505803

Database

Identifier

Smiles:

CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

Inchikey:

AYUNIORJHRXIBJ-TXHRRWQRSA-N

Pubchem:

Top molecular features associated with response to 17-AAG

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SIAH3	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	PABPC5	GDSC1000	pan-cancer	AAC	-0.12	0.0001
mRNA	NPAT	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	GAB2	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	STIM2	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	ANK2	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	KAZALD1	CCLE	pan-cancer	AAC	0.18	0.0001
mRNA	GPX1	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	NT5M	CCLE	pan-cancer	AAC	-0.19	0.0001
mRNA	MGST1	CCLE	pan-cancer	AAC	0.19	0.0001