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SB 216763

SB 216763

Synonyms

Sources	Names Used
GDSC1000	SB 216763
PharmacoGx	SB 216763

External IDs

Database	Identifier
Smiles:	Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem:	176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB 216763

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	VPS72	GDSC1000	pan-cancer	AAC	-0.071	0.07
mRNA	ZNF70	GDSC1000	pan-cancer	AAC	0.07	0.07
mRNA	CCL3	GDSC1000	pan-cancer	AAC	-0.074	0.07
mRNA	C10orf82	GDSC1000	pan-cancer	AAC	-0.067	0.07
mRNA	APEH	GDSC1000	pan-cancer	AAC	0.071	0.07
mRNA	USP16	GDSC1000	pan-cancer	AAC	-0.072	0.07
mRNA	CTNNA1	GDSC1000	pan-cancer	AAC	0.086	0.07
mRNA	ZNF813	GDSC1000	pan-cancer	AAC	-0.071	0.07
mRNA	SMURF2	GDSC1000	pan-cancer	AAC	0.075	0.07
mRNA	TMEM106C	GDSC1000	pan-cancer	AAC	-0.07	0.07

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