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SB 216763

SB 216763

Synonyms

Sources	Names Used
GDSC1000	SB 216763
PharmacoGx	SB 216763

External IDs

Database	Identifier
Smiles:	Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem:	176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB 216763

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CYTH3	GDSC1000	pan-cancer	AAC	0.076	0.07
mRNA	FOXB1	GDSC1000	pan-cancer	AAC	-0.068	0.07
mRNA	ARRB1	GDSC1000	pan-cancer	AAC	0.069	0.07
mRNA	HMBS	GDSC1000	pan-cancer	AAC	0.068	0.07
mRNA	HES6	GDSC1000	pan-cancer	AAC	-0.073	0.07
mRNA	HTRA4	GDSC1000	pan-cancer	AAC	0.071	0.07
mRNA	ISG20L2	GDSC1000	pan-cancer	AAC	-0.071	0.07
mRNA	LIF	GDSC1000	pan-cancer	AAC	0.079	0.07
mRNA	ARHGAP36	GDSC1000	pan-cancer	AAC	-0.078	0.07
mRNA	TMEM266	GDSC1000	pan-cancer	AAC	-0.071	0.07

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