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SB 216763

SB 216763

Synonyms

Sources	Names Used
GDSC1000	SB 216763
PharmacoGx	SB 216763

External IDs

Database	Identifier
Smiles:	Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem:	176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB 216763

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SETD9	GDSC1000	pan-cancer	AAC	0.12	0.001
mRNA	SEC61B	GDSC1000	pan-cancer	AAC	-0.12	0.001
mRNA	EIF2AK4	GDSC1000	pan-cancer	AAC	0.13	0.001
mRNA	SUZ12	GDSC1000	pan-cancer	AAC	-0.14	0.001
mRNA	SYN1	GDSC1000	pan-cancer	AAC	-0.13	0.001
mRNA	ME1	GDSC1000	pan-cancer	AAC	0.14	0.001
mRNA	COX7B	GDSC1000	pan-cancer	AAC	-0.12	0.001
mRNA	ZNF546	GDSC1000	pan-cancer	AAC	0.13	0.001
mRNA	SYNE2	GDSC1000	pan-cancer	AAC	-0.12	0.001
mRNA	VBP1	GDSC1000	pan-cancer	AAC	-0.12	0.001

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