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SB 216763

SB 216763

Synonyms

Sources	Names Used
GDSC1000	SB 216763
PharmacoGx	SB 216763

External IDs

Database	Identifier
Smiles:	Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem:	176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB 216763

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SLC25A44	GDSC1000	pan-cancer	AAC	-0.13	0.001
mRNA	MAN2C1	GDSC1000	pan-cancer	AAC	0.12	0.001
mRNA	FAM129B	GDSC1000	pan-cancer	AAC	0.2	0.001
mRNA	FAM193A	GDSC1000	pan-cancer	AAC	-0.13	0.001
mRNA	TSPYL2	GDSC1000	pan-cancer	AAC	-0.12	0.001
mRNA	AMER3	GDSC1000	pan-cancer	AAC	-0.13	0.001
mRNA	C1QA	GDSC1000	pan-cancer	AAC	-0.13	0.001
mRNA	SPOCD1	GDSC1000	pan-cancer	AAC	0.14	0.001
mRNA	IZUMO1R	GDSC1000	pan-cancer	AAC	-0.12	0.001
mRNA	ZNF81	GDSC1000	pan-cancer	AAC	-0.12	0.001

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