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SB 216763

SB 216763

Synonyms

Sources	Names Used
GDSC1000	SB 216763
PharmacoGx	SB 216763

External IDs

Database	Identifier
Smiles:	Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem:	176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB 216763

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRPF3	GDSC1000	pan-cancer	AAC	-0.14	0.0004
mRNA	TXK	GDSC1000	pan-cancer	AAC	0.14	0.0004
mRNA	GPAM	GDSC1000	pan-cancer	AAC	0.14	0.0004
mRNA	PRRC2C	GDSC1000	pan-cancer	AAC	-0.14	0.0005
mRNA	AHR	GDSC1000	pan-cancer	AAC	0.15	0.0005
mRNA	SERPINH1	GDSC1000	pan-cancer	AAC	0.16	0.0005
mRNA	SIX3	GDSC1000	pan-cancer	AAC	-0.14	0.0006
mRNA	EMILIN3	GDSC1000	pan-cancer	AAC	-0.13	0.0006
mRNA	CYR61	GDSC1000	pan-cancer	AAC	0.19	0.0006
mRNA	AP5M1	GDSC1000	pan-cancer	AAC	-0.14	0.0006

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