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Axitinib

Synonyms

SourcesNames Used
GDSC1000, FIMMAxitinib
CTRPv2axitinib
PharmacoGx Axitinib

External IDs

DatabaseIdentifier
Smiles: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey: RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem: 6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Axitinib


Feature TypeStandardized
Nominal ANOVA
mRNA PDGFRA CTRPv2 pan-cancer AAC 0.26 6e-15
mRNA KIAA1586 CTRPv2 pan-cancer AAC 0.28 2e-14
mRNA CISH CTRPv2 pan-cancer AAC 0.26 4e-14
mRNA KLF1 GDSC1000 pan-cancer AAC 0.26 5e-14
mRNA PTPN7 CTRPv2 pan-cancer AAC 0.35 1e-13
mRNA SIGLEC6 GDSC1000 pan-cancer AAC 0.25 3e-13
mRNA GBGT1 GDSC1000 pan-cancer AAC 0.26 3e-13
mRNA RHD GDSC1000 pan-cancer AAC 0.25 1e-12
mRNA ZNF445 CTRPv2 pan-cancer AAC 0.27 3e-12
mRNA SPN CTRPv2 pan-cancer AAC 0.32 3e-12
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