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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF618 CTRPv2 pan-cancer AAC 0.22 1e-09
mRNA ZNF737 CTRPv2 pan-cancer AAC 0.22 1e-09
mRNA PIKFYVE CTRPv2 pan-cancer AAC 0.25 2e-09
mRNA SOX4 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA PARP15 CTRPv2 pan-cancer AAC 0.22 2e-09
mRNA PLEKHO1 CTRPv2 pan-cancer AAC 0.23 2e-09
mRNA ZNF738 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA ZNF669 CTRPv2 pan-cancer AAC 0.22 2e-09
mRNA SCAF4 CTRPv2 pan-cancer AAC 0.24 3e-09
mRNA CBX2 CTRPv2 pan-cancer AAC 0.23 3e-09
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