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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA CHD3 CTRPv2 pan-cancer AAC 0.24 3e-11
mRNA BCL7A CTRPv2 pan-cancer AAC 0.25 3e-11
mRNA TOP2B CTRPv2 pan-cancer AAC 0.25 4e-11
mRNA SLFN11 CTRPv2 pan-cancer AAC 0.24 6e-11
mRNA TIA1 CTRPv2 pan-cancer AAC 0.23 7e-11
mRNA LUC7L CTRPv2 pan-cancer AAC 0.25 8e-11
mRNA TCF3 CTRPv2 pan-cancer AAC 0.27 8e-11
mRNA ZNF491 CTRPv2 pan-cancer AAC 0.23 9e-11
mRNA MDM4 CTRPv2 pan-cancer AAC 0.26 1e-10
mRNA HNRNPA1 CTRPv2 pan-cancer AAC 0.25 2e-10
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