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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA YPEL1 CTRPv2 pan-cancer AAC 0.27 4e-14
mRNA RSBN1 CTRPv2 pan-cancer AAC 0.27 1e-13
mRNA KIAA0922 CTRPv2 pan-cancer AAC 0.29 2e-13
mRNA MSH6 CTRPv2 pan-cancer AAC 0.25 1e-12
mRNA UHRF1 CTRPv2 pan-cancer AAC 0.25 1e-12
mRNA FAM117B CTRPv2 pan-cancer AAC 0.26 2e-12
mRNA GPC2 CTRPv2 pan-cancer AAC 0.28 1e-11
mRNA MEX3A CTRPv2 pan-cancer AAC 0.28 3e-11
mRNA EBF1 CTRPv2 pan-cancer AAC 0.23 3e-11
mRNA WASF1 CTRPv2 pan-cancer AAC 0.25 3e-11
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