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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA LTBR GDSC1000 pan-cancer AAC 0.34 7e-19
mRNA LGALS3 GDSC1000 pan-cancer AAC 0.31 2e-18
mRNA ANXA4 GDSC1000 pan-cancer AAC 0.32 5e-18
mRNA RAB39B GDSC1000 pan-cancer AAC -0.29 7e-18
mRNA CLIC1 GDSC1000 pan-cancer AAC 0.27 1e-17
mRNA CST3 GDSC1000 pan-cancer AAC 0.31 2e-17
mRNA SLC35D2 GDSC1000 pan-cancer AAC 0.34 3e-17
mRNA TMBIM1 GDSC1000 pan-cancer AAC 0.3 3e-17
mRNA LGALS1 GDSC1000 pan-cancer AAC 0.28 4e-17
mRNA S100A6 GDSC1000 pan-cancer AAC 0.3 5e-17
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