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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGAP12 GDSC1000 pan-cancer AAC 0.14 7e-05
mRNA C1QL1 GDSC1000 pan-cancer AAC -0.14 7e-05
mRNA DVL2 GDSC1000 pan-cancer AAC -0.12 7e-05
mRNA DNAJB12 GDSC1000 pan-cancer AAC 0.12 7e-05
mRNA INPP5A GDSC1000 pan-cancer AAC 0.13 7e-05
mRNA HACE1 GDSC1000 pan-cancer AAC -0.12 7e-05
mRNA ARX GDSC1000 pan-cancer AAC -0.13 7e-05
mRNA POC5 GDSC1000 pan-cancer AAC -0.14 7e-05
mRNA C10orf35 GDSC1000 pan-cancer AAC -0.16 7e-05
mRNA DRG1 GDSC1000 pan-cancer AAC -0.12 7e-05
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