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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA ARF5 GDSC1000 pan-cancer AAC -0.12 6e-05
mRNA MMP8 GDSC1000 pan-cancer AAC 0.15 6e-05
mRNA UBE2D2 GDSC1000 pan-cancer AAC -0.13 6e-05
mRNA C9orf69 GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA ALKBH2 GDSC1000 pan-cancer AAC -0.13 6e-05
mRNA S100A7L2 GDSC1000 pan-cancer AAC -0.12 6e-05
mRNA PTPN9 GDSC1000 pan-cancer AAC 0.12 6e-05
mRNA GALNT2 GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA TMBIM6 GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA GLRA3 GDSC1000 pan-cancer AAC -0.12 6e-05
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