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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA CALD1 GDSC1000 pan-cancer AAC 0.17 5e-05
mRNA DOLPP1 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA ZDHHC15 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA SIL1 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA RBBP4 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA NTN4 GDSC1000 pan-cancer AAC 0.15 5e-05
mRNA IFT140 GDSC1000 pan-cancer AAC -0.12 5e-05
mRNA MAGEH1 GDSC1000 pan-cancer AAC -0.14 5e-05
mRNA BLVRB GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA TCTN3 GDSC1000 pan-cancer AAC 0.12 5e-05
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