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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA XPO5 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA ZBTB8OS GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA TCEAL2 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA THOC7 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA RAB9B GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA LRRN3 GDSC1000 pan-cancer AAC -0.15 5e-05
mRNA LPAR4 FIMM pan-cancer AAC 0.76 5e-05
mRNA AMER3 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA FAM212B GDSC1000 pan-cancer AAC -0.12 5e-05
mRNA SHC4 GDSC1000 pan-cancer AAC 0.16 5e-05
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