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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA ACAA1 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA KMT2E GDSC1000 pan-cancer AAC -0.13 4e-05
mRNA CDH7 GDSC1000 pan-cancer AAC -0.13 4e-05
mRNA ARF4 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA CHRNA3 GDSC1000 pan-cancer AAC -0.2 4e-05
mRNA FLII GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA EVPL GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA PYHIN1 GDSC1000 pan-cancer AAC -0.14 4e-05
mRNA TCP10L GDSC1000 pan-cancer AAC -0.12 4e-05
mRNA MCM2 GDSC1000 pan-cancer AAC -0.13 4e-05
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