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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA NPAS2 GDSC1000 pan-cancer AAC 0.23 1e-12
mRNA RAB32 GDSC1000 pan-cancer AAC 0.25 1e-12
mRNA MYOF GDSC1000 pan-cancer AAC 0.29 1e-12
mRNA ZNF682 GDSC1000 pan-cancer AAC -0.22 1e-12
mRNA SUCLG2 GDSC1000 pan-cancer AAC 0.23 2e-12
mRNA CRTAP GDSC1000 pan-cancer AAC 0.24 2e-12
mRNA ITGA2 GDSC1000 pan-cancer AAC 0.27 2e-12
mRNA CARMIL2 GDSC1000 pan-cancer AAC -0.26 2e-12
mRNA ZNF738 GDSC1000 pan-cancer AAC -0.22 2e-12
mRNA EOGT GDSC1000 pan-cancer AAC 0.21 2e-12
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