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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA EMC9 GDSC1000 pan-cancer AAC -0.22 9e-13
mRNA MLKL GDSC1000 pan-cancer AAC 0.23 9e-13
mRNA ETV5 GDSC1000 pan-cancer AAC 0.23 9e-13
mRNA TNFRSF12A GDSC1000 pan-cancer AAC 0.32 1e-12
mRNA DUSP26 GDSC1000 pan-cancer AAC -0.24 1e-12
mRNA TXNDC16 GDSC1000 pan-cancer AAC -0.23 1e-12
mRNA NELL2 GDSC1000 pan-cancer AAC -0.24 1e-12
mRNA LPCAT2 GDSC1000 pan-cancer AAC 0.23 1e-12
mRNA KIAA0930 GDSC1000 pan-cancer AAC 0.22 1e-12
mRNA RNASE2 GDSC1000 pan-cancer AAC 0.22 1e-12
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