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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA INIP GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA INPP5J GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA SYN2 GDSC1000 pan-cancer AAC -0.18 2e-07
mRNA CDCA5 GDSC1000 pan-cancer AAC -0.16 2e-07
mRNA ZNF91 GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA IL18 GDSC1000 pan-cancer AAC 0.19 2e-07
mRNA SPIB GDSC1000 pan-cancer AAC -0.18 2e-07
mRNA MGST1 GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA SNX22 GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA SEC61A2 GDSC1000 pan-cancer AAC -0.16 2e-07
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