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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA NABP2 GDSC1000 pan-cancer AAC -0.16 8e-08
mRNA SLC22A18 GDSC1000 pan-cancer AAC 0.19 8e-08
mRNA GPR137C GDSC1000 pan-cancer AAC -0.18 8e-08
mRNA S100B GDSC1000 pan-cancer AAC 0.24 8e-08
mRNA ENOPH1 GDSC1000 pan-cancer AAC -0.17 8e-08
mRNA NUDT13 GDSC1000 pan-cancer AAC 0.16 8e-08
mRNA PQLC3 GDSC1000 pan-cancer AAC 0.17 8e-08
mRNA SMAD3 GDSC1000 pan-cancer AAC 0.18 8e-08
mRNA SKAP2 GDSC1000 pan-cancer AAC 0.18 8e-08
mRNA CPT1C GDSC1000 pan-cancer AAC -0.19 8e-08
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