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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA ANXA1 GDSC1000 pan-cancer AAC 0.27 2e-14
mRNA PHLDA1 GDSC1000 pan-cancer AAC 0.29 3e-14
mRNA PYGL GDSC1000 pan-cancer AAC 0.25 3e-14
mRNA TNFRSF1A GDSC1000 pan-cancer AAC 0.25 4e-14
mRNA ITGB5 GDSC1000 pan-cancer AAC 0.29 4e-14
mRNA C16orf87 GDSC1000 pan-cancer AAC -0.25 5e-14
mRNA RALB GDSC1000 pan-cancer AAC 0.24 5e-14
mRNA PON2 GDSC1000 pan-cancer AAC 0.29 6e-14
mRNA OAF GDSC1000 pan-cancer AAC 0.25 6e-14
mRNA MYO1F GDSC1000 pan-cancer AAC 0.25 9e-14
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