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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA RNPEPL1 GDSC1000 pan-cancer AAC 0.18 4e-08
mRNA WHSC1 GDSC1000 pan-cancer AAC -0.18 4e-08
mRNA BHLHE40 GDSC1000 pan-cancer AAC 0.18 4e-08
mRNA KIAA0922 GDSC1000 pan-cancer AAC -0.21 4e-08
mRNA TMEM2 GDSC1000 pan-cancer AAC 0.19 4e-08
mRNA PARVA GDSC1000 pan-cancer AAC 0.23 4e-08
mRNA CYGB GDSC1000 pan-cancer AAC 0.19 4e-08
mRNA SLC20A1 GDSC1000 pan-cancer AAC 0.17 4e-08
mRNA INPP4B GDSC1000 pan-cancer AAC 0.18 4e-08
mRNA SOCS4 GDSC1000 pan-cancer AAC -0.17 4e-08
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