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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA C1orf109 GDSC1000 pan-cancer AAC -0.17 3e-08
mRNA ZNF681 GDSC1000 pan-cancer AAC -0.17 3e-08
mRNA GRIK3 GDSC1000 pan-cancer AAC -0.17 3e-08
mRNA UNC79 GDSC1000 pan-cancer AAC -0.18 3e-08
mRNA WNK3 GDSC1000 pan-cancer AAC -0.19 3e-08
mRNA KIF5A GDSC1000 pan-cancer AAC -0.18 3e-08
mRNA SAMD9 GDSC1000 pan-cancer AAC 0.18 3e-08
mRNA SMIM8 GDSC1000 pan-cancer AAC -0.18 3e-08
mRNA NCOA4 GDSC1000 pan-cancer AAC 0.18 3e-08
mRNA SENP1 GDSC1000 pan-cancer AAC -0.18 3e-08
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