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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA CTSZ GDSC1000 pan-cancer AAC 0.18 2e-08
mRNA MTMR11 GDSC1000 pan-cancer AAC 0.18 2e-08
mRNA MLANA GDSC1000 pan-cancer AAC 0.23 2e-08
mRNA KCNN4 GDSC1000 pan-cancer AAC 0.17 2e-08
mRNA MFSD12 GDSC1000 pan-cancer AAC 0.21 2e-08
mRNA GBE1 GDSC1000 pan-cancer AAC 0.19 2e-08
mRNA EMSY GDSC1000 pan-cancer AAC -0.17 3e-08
mRNA KCNAB3 GDSC1000 pan-cancer AAC -0.18 3e-08
mRNA RETSAT GDSC1000 pan-cancer AAC 0.19 3e-08
mRNA ATF5 GDSC1000 pan-cancer AAC -0.19 3e-08
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