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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA CAPN2 GDSC1000 pan-cancer AAC 0.32 2e-15
mRNA B3GNTL1 GDSC1000 pan-cancer AAC 0.24 3e-15
mRNA PLAUR GDSC1000 pan-cancer AAC 0.26 3e-15
mRNA FXYD5 GDSC1000 pan-cancer AAC 0.26 3e-15
mRNA SNX9 GDSC1000 pan-cancer AAC 0.31 4e-15
mRNA SBK1 GDSC1000 pan-cancer AAC -0.27 4e-15
mRNA KIF5C GDSC1000 pan-cancer AAC -0.26 4e-15
mRNA SFXN3 GDSC1000 pan-cancer AAC 0.26 7e-15
mRNA FUCA2 GDSC1000 pan-cancer AAC 0.27 2e-14
mRNA LYZ GDSC1000 pan-cancer AAC 0.25 2e-14
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