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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA BIN2 GDSC1000 pan-cancer AAC 0.24 5e-09
mRNA FAM184A GDSC1000 pan-cancer AAC -0.2 5e-09
mRNA SHC1 GDSC1000 pan-cancer AAC 0.2 5e-09
mRNA CTSG GDSC1000 pan-cancer AAC 0.19 6e-09
mRNA AKAP8L GDSC1000 pan-cancer AAC -0.19 6e-09
mRNA TLR2 GDSC1000 pan-cancer AAC 0.18 6e-09
mRNA ENG GDSC1000 pan-cancer AAC 0.19 6e-09
mRNA RHOH GDSC1000 pan-cancer AAC -0.28 6e-09
mRNA PLOD3 GDSC1000 pan-cancer AAC 0.22 6e-09
mRNA CTBS GDSC1000 pan-cancer AAC 0.17 6e-09
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