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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA HADHB GDSC1000 pan-cancer AAC 0.18 4e-09
mRNA UCP2 GDSC1000 pan-cancer AAC -0.2 4e-09
mRNA HAS2 GDSC1000 pan-cancer AAC 0.19 5e-09
mRNA IFITM3 GDSC1000 pan-cancer AAC 0.23 5e-09
mRNA ITGB1 GDSC1000 pan-cancer AAC 0.22 5e-09
mRNA CMTM3 GDSC1000 pan-cancer AAC 0.19 5e-09
mRNA EMILIN2 GDSC1000 pan-cancer AAC 0.18 5e-09
mRNA CEP97 GDSC1000 pan-cancer AAC -0.18 5e-09
mRNA INA GDSC1000 pan-cancer AAC -0.21 5e-09
mRNA PDE6B GDSC1000 pan-cancer AAC -0.18 5e-09
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