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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA PROCR GDSC1000 pan-cancer AAC 0.21 1e-09
mRNA HSPG2 GDSC1000 pan-cancer AAC 0.21 1e-09
mRNA PIWIL4 GDSC1000 pan-cancer AAC 0.2 1e-09
mRNA SSBP2 GDSC1000 pan-cancer AAC -0.22 1e-09
mRNA SEC11A GDSC1000 pan-cancer AAC 0.18 1e-09
mRNA UCN2 GDSC1000 pan-cancer AAC 0.21 2e-09
mRNA FBXO10 GDSC1000 pan-cancer AAC -0.2 2e-09
mRNA SULT4A1 GDSC1000 pan-cancer AAC -0.21 2e-09
mRNA OGFOD3 GDSC1000 pan-cancer AAC 0.18 2e-09
mRNA PHF8 GDSC1000 pan-cancer AAC -0.2 2e-09
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