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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM173 GDSC1000 pan-cancer AAC 0.19 1e-09
mRNA PTGR1 GDSC1000 pan-cancer AAC 0.25 1e-09
mRNA CELF1 GDSC1000 pan-cancer AAC -0.2 1e-09
mRNA H6PD GDSC1000 pan-cancer AAC 0.18 1e-09
mRNA GPX1 GDSC1000 pan-cancer AAC 0.18 1e-09
mRNA CD72 GDSC1000 pan-cancer AAC -0.21 1e-09
mRNA CRMP1 GDSC1000 pan-cancer AAC -0.21 1e-09
mRNA ZNF138 GDSC1000 pan-cancer AAC -0.2 1e-09
mRNA RFX8 GDSC1000 pan-cancer AAC 0.19 1e-09
mRNA NPC2 GDSC1000 pan-cancer AAC 0.21 1e-09
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