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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA SPATS2L GDSC1000 pan-cancer AAC 0.23 9e-10
mRNA KIAA1324L GDSC1000 pan-cancer AAC -0.19 9e-10
mRNA GNG12 GDSC1000 pan-cancer AAC 0.28 1e-09
mRNA SAP30 GDSC1000 pan-cancer AAC -0.22 1e-09
mRNA ETHE1 GDSC1000 pan-cancer AAC 0.2 1e-09
mRNA NAPB GDSC1000 pan-cancer AAC -0.19 1e-09
mRNA CD79B GDSC1000 pan-cancer AAC -0.22 1e-09
mRNA CCP110 GDSC1000 pan-cancer AAC -0.2 1e-09
mRNA BCOR GDSC1000 pan-cancer AAC -0.21 1e-09
mRNA GEMIN2 GDSC1000 pan-cancer AAC -0.2 1e-09
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