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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA INSM1 GDSC1000 pan-cancer AAC -0.2 8e-10
mRNA KLHL32 GDSC1000 pan-cancer AAC -0.19 8e-10
mRNA DRAM1 GDSC1000 pan-cancer AAC 0.21 8e-10
mRNA SIT1 GDSC1000 pan-cancer AAC -0.23 8e-10
mRNA MZB1 GDSC1000 pan-cancer AAC -0.27 8e-10
mRNA HECTD4 GDSC1000 pan-cancer AAC -0.2 9e-10
mRNA TSPAN33 GDSC1000 pan-cancer AAC -0.2 9e-10
mRNA RASA3 GDSC1000 pan-cancer AAC 0.19 9e-10
mRNA AZU1 GDSC1000 pan-cancer AAC 0.19 9e-10
mRNA CATSPER1 GDSC1000 pan-cancer AAC 0.19 9e-10
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