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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA LGALS12 GDSC1000 pan-cancer AAC 0.19 5e-10
mRNA CARD6 GDSC1000 pan-cancer AAC 0.19 5e-10
mRNA ACCS GDSC1000 pan-cancer AAC 0.19 6e-10
mRNA MS4A6A GDSC1000 pan-cancer AAC 0.19 6e-10
mRNA ARL6IP5 GDSC1000 pan-cancer AAC 0.19 7e-10
mRNA GBGT1 GDSC1000 pan-cancer AAC 0.19 7e-10
mRNA TSPAN32 GDSC1000 pan-cancer AAC 0.2 7e-10
mRNA PDRG1 GDSC1000 pan-cancer AAC -0.18 7e-10
mRNA POU2AF1 GDSC1000 pan-cancer AAC -0.25 7e-10
mRNA ZBTB5 GDSC1000 pan-cancer AAC -0.19 7e-10
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