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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA ITGA6 GDSC1000 pan-cancer AAC 0.25 5e-10
mRNA C9orf72 GDSC1000 pan-cancer AAC -0.2 5e-10
mRNA MAP4K1 GDSC1000 pan-cancer AAC -0.28 5e-10
mRNA QSOX1 GDSC1000 pan-cancer AAC 0.21 5e-10
mRNA TRIM21 GDSC1000 pan-cancer AAC 0.21 5e-10
mRNA GCSAM GDSC1000 pan-cancer AAC -0.24 5e-10
mRNA CD58 GDSC1000 pan-cancer AAC 0.19 5e-10
mRNA CMTM7 GDSC1000 pan-cancer AAC 0.2 5e-10
mRNA GSTO1 GDSC1000 pan-cancer AAC 0.19 5e-10
mRNA ANTXR2 GDSC1000 pan-cancer AAC 0.19 5e-10
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