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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA STK10 GDSC1000 pan-cancer AAC 0.25 4e-10
mRNA SIRPA GDSC1000 pan-cancer AAC 0.23 4e-10
mRNA CD151 GDSC1000 pan-cancer AAC 0.25 4e-10
mRNA BEND4 GDSC1000 pan-cancer AAC -0.22 4e-10
mRNA PRDM2 GDSC1000 pan-cancer AAC -0.23 4e-10
mRNA NRSN1 GDSC1000 pan-cancer AAC -0.22 4e-10
mRNA TCF3 GDSC1000 pan-cancer AAC -0.23 4e-10
mRNA GALE GDSC1000 pan-cancer AAC 0.22 4e-10
mRNA MAPKAPK3 GDSC1000 pan-cancer AAC 0.19 4e-10
mRNA SYNE2 GDSC1000 pan-cancer AAC -0.19 4e-10
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